SIGMA-Aldrich has introduced the Precisio Kinases collection of active kinases which have been designed to enable scientists to achieve greater insight into protein phosphorylation and cell signalling.
Sigma-Aldrich believes Precisio Kinases allow for the characterisation of cellular processes and may contribute to new therapeutic strategies for treating diseases including cancer, diabetes and hypertension.
Protein kinases aid mediating signal transduction in development, transcription, immune response, metabolism, apoptosis and cell differentiation making them essential in intercellular communication.
Improper kinase function plays a role in many diseases, most notably cancer, and the study of these proteins and their functions may contribute to the discovery and development of new drug targets.